Preheat oven to 400°F (200°C). Line a baking sheet with parchment paper.
In a large bowl, whisk together the flour, sugar, and salt.
Add the dried cranberries and orange zest to the dry ingredients and stir to combine.
Use a pastry blender or your fingers to work the cold butter into the dry ingredients until the mixture resembles coarse crumbs.
In a separate bowl, whisk together the egg, half-and-half, and vanilla extract.
Pour the wet ingredients into the dry ingredients and stir until the dough comes together in a shaggy mass.
Turn the dough out onto a floured surface and gently knead it a few times until it comes together.
Pat the dough into an 8-inch round disk, about 1 inch thick.
Use a sharp knife or pastry cutter to cut the disk into 8-10 wedges.
Place the wedges on the prepared baking sheet, leaving about 1 inch of space between each scone.
Brush the tops of the scones with a little extra half-and-half and sprinkle with granulated sugar.
Bake the scones for 15-20 minutes, or until they are golden brown.